Class EnzymeKinetics

java.lang.Object

org.episteme.natural.biology.biochemistry.EnzymeKinetics

public class EnzymeKinetics
extends Object

Michaelis-Menten enzyme kinetics.

Since:

1.0

Author:

Silvere Martin-Michiellot, Gemini AI (Google DeepMind)

Method Summary

Modifier and Type	Method	Description
static Real	findKm(Real[] substrateConcs, Real[] velocities, Real vMax)	Find Km from velocity data (half-maximal)
static Real[]	lineweaverBurkParams(Real vMax, Real km)	Lineweaver-Burk parameters: {slope, intercept}
static Real	velocity(Real vMax, Real km, Real substrateConc)	Michaelis-Menten: V = Vmax * [S] / (Km + [S])
static Real	velocityWithCompetitiveInhibitor(Real vMax, Real km, Real substrateConc, Real inhibitorConc, Real ki)	Competitive inhibition: V = Vmax * [S] / (Km * (1 + [I]/Ki) + [S])

Methods inherited from class Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Method Details

velocity

public static Real velocity(Real vMax,
 Real km,
 Real substrateConc)

Michaelis-Menten: V = Vmax * [S] / (Km + [S])

lineweaverBurkParams

public static Real[] lineweaverBurkParams(Real vMax,
 Real km)

Lineweaver-Burk parameters: {slope, intercept}

findKm

public static Real findKm(Real[] substrateConcs,
 Real[] velocities,
 Real vMax)

Find Km from velocity data (half-maximal)

velocityWithCompetitiveInhibitor

public static Real velocityWithCompetitiveInhibitor(Real vMax,
 Real km,
 Real substrateConc,
 Real inhibitorConc,
 Real ki)

Competitive inhibition: V = Vmax * [S] / (Km * (1 + [I]/Ki) + [S])